How safe are allergy drops?

  • Allergy drops are very safe. Systemic allergic reactions are rare, occurring in less than 1% of patients. Additionally, a fatality from allergy drops has never been reported. In our practice, patients are given the first dose of the allergy drops in the office. To date, no one that did not have a severe allergic reaction during the in-office challenge has had a significant reaction to the drops at home. Mild allergic reactions to the drops occur with increased frequency. Approximately 5% of patients will experience mild itching or swelling of the mouth and/or mild abdominal discomfort for several minutes after administering the drops. These mild reactions typically resolve within several weeks of starting treatment and usually do not require stopping the drops. In the unlikely event that there is a more severe allergic reaction at home, it is recommended that patients have an Epipen and Benadryl available. We will be adding another blog post soon that takes a deeper dive into the safety of allergy drops.